Total Synthesis of (±)-Cylindricine C
收藏Figshare2016-02-22 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Total_Synthesis_of_Cylindricine_C/2613445
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资源简介：
A concise synthesis of (±)-cylindricine C and its C(13)-epimer is described. Starting from 1-octyne, cylindricine C and 13-epi-cylindricine C were prepared in 11% and 15% yields, respectively. The synthesis involves the preparation of the central tricyclic moiety via a radical α-iodoketone carboazidation/bis-reductive amination sequence. Inversion of the stereochemistry at C(13) and C(5) was efficiently achieved on late stage intermediates.
创建时间：
2016-02-22
