Propagation of DNA methylation through cell division relies on the recognition of methylated cytosines by UHRF1. We present an experimental system where regulation of global and site-specific demethyl
The hypocretin/orexin neuropeptides (hcrt) are key players in the control of sleep and wakefulness evidenced by the fact that lack of hcrt leads to the sleep disorder Narcolepsy Type 1. Sleep disturba
In this study we show that global levels of mature miRNAs are unaffected in C. elegans after knockdown of either subunit of CK2 (encoded by kin-3 and kin-10) by RNAi. Small RNAs were quantified from w
Data was recorded using silicon probe electrodes in the frontal cortices of male Long Evans rats between 4-7 months of age. The design was to have no specific behavior, task or stimulus, rather the an
Medulloblastoma (MB) is the most common malignant pediatric brain tumor. MB is classified into four primary molecular subgroups: wingless (WNT), sonic hedgehog (SHH), Group 3 (G3), and Group 4 (G4), a
