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Crystal structure of EGFR with mutant-selective dihydrodibenzodiazepinone allosteric inhibitor

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Crystal structure of EGFR with mutant-selective dihydrodibenzodiazepinone allosteric inhibitor Descriptor: 10-benzyl-8-fluoro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one, Epidermal growth factor receptor, MAGNESIUM ION, ... Authors: Heppner, D.E, Eck, M.J. Deposit date: 2019-05-19 Release date: 2019-12-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors. Acs Med.Chem.Lett., 10, 2019
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2019-05-19
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