Data from: Heritable differences in abundance of bacterial rhizosphere taxa are correlated with fungal necrotrophic pathogen resistance

This Ag Data Commons submission includes the 94 sunflower paired-end sequencing FASTQ files, the corresponding 16S bacterial FASTQ files, and other relevant data to the study described below:
Host-microbe interactions are increasingly recognized as important drivers of organismal health, growth, longevity, and community-scale ecological processes. However, less is known about how genetic variation affects hosts' associated microbiomes and downstream phenotypes. We demonstrate that sunflower Helianthus annuus harbors substantial, heritable variation in microbial communities under field conditions. We show that microbial communities co-vary with heritable variation in resistance to root infection caused by the necrotrophic pathogen Sclerotinia sclerotiorum, and that plants grown in autoclaved soil showed almost complete elimination of pathogen resistance. Association mapping suggests at least 59 genetic locations with effects on both microbial relative abundance and Sclerotinia resistance. Although the genetic architecture appears quantitative, we have elucidated previously unexplained genetic variation for resistance to this pathogen. We identify new targets for plant breeding and demonstrate the potential for heritable microbial associations to play important roles in defense in natural and human-altered environments.
See README for details of each table in the spreadsheet and related information.

本 Ag Data Commons 提交包含 94 个向日葵配对末端测序 FASTQ 文件、相应的 16S 细菌 FASTQ 文件以及与以下描述的研究相关的其他数据。宿主-微生物相互作用日益被认为是影响生物体健康、生长、寿命以及群落尺度生态过程的重要因素。然而，关于遗传变异如何影响宿主相关微生物组和下游表型的了解却相对有限。本研究表明，在田间条件下，向日葵（Helianthus annuus）的微生物群落具有显著的、可遗传的变异。研究还发现，微生物群落与宿主对由腐生病原菌 Sclerotinia sclerotiorum 引起的根部感染的抗性遗传变异呈共变。在高压灭菌土壤中生长的植物几乎完全丧失了对病原菌的抗性。关联图谱分析表明，至少存在 59 个对微生物相对丰度和 Sclerotinia 抗性有影响的遗传位点。尽管遗传结构看似呈数量性状，但我们已阐明了此前未解释的该病原菌抗性的遗传变异。本研究确定了植物育种的新靶点，并展示了可遗传微生物关联在自然环境和人为改变的环境中发挥重要防御作用的潜力。详见 README 文件以获取电子表格中每个表格的详细信息及相关信息。