Crystal structure of PDE10A2 with fragment ZT0449 (5-nitro-1H-benzimidazole)
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Crystal structure of PDE10A2 with fragment ZT0449 (5-nitro-1H-benzimidazole) Descriptor: 5-nitro-1H-benzimidazole, NICKEL (II) ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Authors: Sridar, V, Badger, J, Logan, C, Chie-Leon, B, Nienaber, V. Deposit date: 2013-09-18 Release date: 2014-05-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography. J Biomol Screen, 19, 2014
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2013-09-18
