Utility files and datasets for "Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport"

NPC Simulations Utility Files and Datasets User's Manual and Tutorial A detailed User's Manual in PDF format and a Tutorial in Jupyter Notebook format are available in this folder. Scripts/ Utility scripts used for initiating and analyzing the simulation. See tutorial for details on how and when to use key scripts. Models/NPC2018/ Kim et al. 2018 model of the NPC scaffold used in this work Data/CryoET/ In situ cryo-electron tomography (cryoET) map of the NPC's central channel used for validation of simulated NPC morphology Reference Raveh B*, Eliasian R, Rashkovits S, Russel D, Hayama R, Sparks SE, Singh D, Lim R, Villa E, Rout MP*, Cowburn D*, Sali A*. Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport. Proc Nat Acad Sci (2025), in press. License See LICENSE file.