Left ventricular function.
收藏Figshare2026-03-11 更新2026-04-28 收录
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BackgroundAlthough surgical repair of aortic coarctation (CoA) often restores hemodynamic integrity, subclinical myocardial dysfunction may persist long-term. Left atrial (LA) strain is a sensitive marker of atrial compliance and early diastolic dysfunction, but its role in pediatric CoA is underexplored.MethodsThe study was a multicenter, cross-sectional, observational study conducted at three tertiary hospitals in Vietnam. We enrolled 34 children with isolated CoA who underwent successful surgical repair, recruited between December 2022 and March 2025. LA volumes and strain, with LA reservoir strain (LASr) as the primary parameter, were assessed by two-dimensional speckle-tracking echocardiography. Values were compared with published pediatric reference data. Left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) were also measured.ResultsDespite preserved LVEF and normal anatomy, mean LASr was significantly reduced in the CoA group (37.6 ± 6.2%) compared to reference values (47.3%; p ConclusionsSubclinical left atrial dysfunction is common in children after successful CoA repair, even in the absence of residual obstruction or systolic impairment. Measuring LA strain may provide incremental value for early risk stratification and long-term follow-up in this population.
创建时间:
2026-03-11



