Body weight, fasting insulin and glucose of female wild type (WT) and Trpm5-/- (KO) mice at different time points when fed HFD or cafeteria diet.

The mice were fed the high caloric diets from the age of 12 weeks (w. 0). The week notation then corresponds to number of weeks being on respective diets. To determine whether effects on glucose and insulin homeostasis were directly dependent of the weight gain, the later time points chosen for the oral glucose tolerance test (OGTT) was when the Trpm5-/- mice had reached the same bodyweight as the wild type mice at the preceding OGTT. Arrows indicates when a similar body weight was reached. Data are presented as mean ± SEM.***p***pTrpm5-/- vs corresponding wild type control at the same age within respective diet (students t-test).apcpTrpm5-/- vs corresponding wild type control at a similar body weight within respective diet (students t-test).Body weight, fasting insulin and glucose of female wild type (WT) and Trpm5-/- (KO) mice at different time points when fed HFD or cafeteria diet.