E-MTAB-5470

NIAID Data Ecosystem2026-04-18 收录

果蝇翅膀成虫盘转录组

MYC基因调控

数据链接：

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资源简介：

Myc-dependent transcriptome of Drosophila L3 larval wing imaginal discs, and its dependency on Max and/or the PAF1 complex component Atu/Leo1

创建时间：

2019-05-14

OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors

MYC基因调控

OmoMYC抗肿瘤机制

MYC genes have both essential roles during normal development and exert oncogenic functions during tumorigenesis. Expression of a dominant-negative allele of MYC, termed OmoMYC, can induce rapid tumor

NIAID Data Ecosystem50

RNA-seq analysis of HeLa cells following MYC inhibition with ASO

转录组分析

MYC基因调控

We performed RNA-seq on HeLa cells treated with MYCASO-3, a non-targeting ASO (NT-ASO), Lipofectamine alone, and untreated cells Overall design: Cells were treated for 4h or 18h with 10 nM ASO (formul

NIAID Data Ecosystem30

MYC Amplifies Gene Expression through Global Changes in Transcription Factor Dynamics

MYC基因调控

基因表达动力学

The MYC oncogene has been studied for decades, yet there is still intense debate over how this transcription factor controls gene expression. Here, we seek to answer these questions with an in vivo re

NIAID Data Ecosystem20

The WNT-dependent gating of MYC requires non-canonical functions of a distal CTCF binding site (RNA-Seq II)

WNT信号通路

MYC基因调控

Abnormal WNT signaling increases MYC expression in colon cancer cells in part via oncogenic super-enhancer-(OSE)-mediated gating of the active MYC to the nuclear pore in a poorly understood process. W

NIAID Data Ecosystem30

Myc influences metastatic heterogeneity in pancreatic cancer.

胰腺癌转移

MYC基因调控

Myc influences metastatic heterogeneity in pancreatic cancer.

NIAID Data Ecosystem20