Enrichment of CVS tissue-specific isoforms for RBP binding sites.

For each pairwise comparison between CVS tissues (columns A and B), the table shows the differences in the overlap with each eCLIP experiment [31] between the gene bodies of isoforms specific to one of the two tested CVS tissues and the gene bodies of isoforms that are not differentially expressed. Enrichments were performed using increasingly stringent thresholds for determining CVS tissue-specific isoforms, based on the log2 ratio between the mean isoform usage in the two tested CVS tissues. The table shows: 1) the two tested CVS tissues (columns A, B); the tested RBP, its associated eCLIP experiment and the cell line in which the eCLIP experiment was performed (columns C-E); the log2 ratio threshold (zero to six, 0.5 increments); and the results obtained from Fisher’s exact test (fisher.test function in R), including the estimate (odds ratio), the log2 of the estimate, and the p-value. Values displayed in this table were used to build Figs 3B and S8.
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