Plasma BDNF independently associated with reverse-dipper pattern of nocturnal blood pressure change.

Multiple logistic regression analyses were performed. The covariates included age, male sex, classical cardiovascular risk factors (body mass index, current smoking, cardiovascular disease history, dyslipidemia, diabetes mellitus, eGFR), medical hypertension treatment (calcium-channel blocker, α or β blocker, ACE inhibitor or ARB, diuretic agent), AHI and BDNF. BDNF was natural logarithm-transformed (ln) to achieve a normal distribution. OR; odds ratio, CI; confidence interval, eGFR; estimated glomerular filtration rate, ACE: angiotensin converting enzyme, ARB; angiotensin receptor blocker, AHI; apnea hypopnea index, BDNF; brain-derived neurotrophic factor.