Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 6
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Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 6 Descriptor: 1'-(2H-indazol-5-ylcarbonyl)-1-(propan-2-yl)-1,4-dihydrospiro[indazole-5,4'-piperidin]-7(6H)-one, Acetyl-CoA carboxylase Authors: Vajdos, F.F. Deposit date: 2014-11-18 Release date: 2014-12-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes. J.Med.Chem., 57, 2014
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2014-11-18



