MCT1-dependent energetic failure and neuroinflammation underlie optic nerve degeneration in Wolfram syndrome mice
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE206150
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Purpose: The goals of this study are to compare NGS-derived retinal transcriptome profiling (RNA-seq) from WT and Wfs1-/- mices. Methods: Retinal mRNA profiles of 240-day-old wild-type (WT) and retina Wolframin knockout (Wfs1−/−) mice were generated by deep sequencing, in triplicate, using Illumina NovaSeq 6000. The sequence reads that passed quality filters were aligned to reference genome Retinal mRNA profiles of 240-day old wild type (WT) and Wfs1-/- mice
创建时间:
2023-02-10



