An investigator-initiated trial to investigate the utility of LUNAR-1 in colorectal cancer patients with resectable distant metastases

Interventions: ctDNA test using LUNAR-1 Blood samples will be taken before surgery (in the case of a two-step surgery, before surgery for metastatic lesions), 28 days after surgery, 12, 24, 36, 48, 60, 72, 84, 96 weeks after surgery. The amount of blood will be 10 mL per test tube, and 4 test tubes will be collected. postoperative adjuvant therapy If the ctDNA test result is negative at 28 days after surgery, postoperative adjuvant therapy will not be administered.;D011379;ctDNA, Adjuvant chemotherapy Primary outcome(s): 1) Negative predictive value in ctDNA-negative patients at 28 days postoperatively. 2) Positive predictive value of ctDNA for recurrence during the postoperative observation period Study Design: single arm study, open(masking not used), historical control, single assignment, screening