Regulatory T cell (T reg) function in HIV exposed seronegative (ESN) individuals
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Regulatory T cell (T reg) function in HIV exposed seronegative (ESN) individuals
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创建时间：
2012-07-18
相关数据集
Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function [ATAC-Seq]. Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function [ATAC-Seq]
We investigated the role of Ikaros in regulatory Tcell identity and function during stimulation using RNA-seq, ATAC-seq, and H3K27ac/Foxp3/Ikzf1 ChIP-seq Overall design: We performed ATAC-seq, RNA-seq
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Human Regulatory T Cell Suppressive Function Is Independent of Apoptosis Induction in Activated Effector T Cells
BackgroundCD4+CD25+FOXP3+ Regulatory T cells (Treg) play a central role in the immune balance to prevent autoimmune disease. One outstanding question is how Tregs suppress effector immune responses in
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Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease. Mus musculus
Regulatory T (Treg) cells suppress the development of inflammatory disease, but our knowledge of transcriptional regulators that control this function remains incomplete. Here we show that expression
NIAID Data Ecosystem30
Transcription profile of WT and LKB1 (encoded by the gene Stk11)-deficient Treg cells. Mus musculus
LKB1 deficiency in Treg cells impairs their survival, metabolism and suppressive function. To exclude the impact of excessive inflammation on LKB1-deficient Treg cells, we generated mixed bone marrow
NIAID Data Ecosystem50
Table_S1_Elevated Numbers of HIV-Specific Poly-Functional CD8+ T Cells With Stem Cell-Like and Follicular Homing Phenotypes in HIV-Exposed Seronegative Individuals.TIFF
HIV-specific CD8+ T cells are known to play a key role in viral control during acute and chronic HIV infection. Although many studies have demonstrated the importance of HIV-specific CD8+ T cells in v
NIAID Data Ecosystem30
