UB-612 Multitope Vaccine Targeting SARS-CoV-2 Spike and Non-Spike Proteins Provides Broad and Durable Immune Responses

NCATS Open Data2022-09-02 更新2026-08-08 收录

多表位疫苗免疫应答

SARS-CoV-2疫苗研究

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https://doi.org/10.1101/2022.08.26.22279232 数据链接链接失效反馈

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UB-612 Multitope Vaccine Targeting SARS-CoV-2 Spike and Non-Spike Proteins Provides Broad and Durable Immune Responses

创建时间：

2022-08-30

A live attenuated vaccine confers superior mucosal and systemic immunity to SARS-CoV-2 variants. A live attenuated vaccine confers superior mucosal and systemic immunity to SARS-CoV-2 variants

疫苗免疫学

SARS-CoV-2疫苗研究

We describe the cellular response to SARS-CoV-2 infections in Syrian hamsters previously immunized with mRNA, Adenovirus, and life-attenuated virus vaccines. Overall design: Two experiments were condu

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DataSheet_1_Optimization of SARS-CoV-2 Spike Protein Expression in the Silkworm and Induction of Efficient Protective Immunity by Inoculation With Alum Adjuvants.pdf

SARS-CoV-2疫苗研究

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The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing a spread of coronavirus disease 2019 (COVID-19) globally. In order to end the COVID-19 pandemic, an effective

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DataSheet_2_Furin and TMPRSS2 Resistant Spike Induces Robust Humoral and Cellular Immunity Against SARS-CoV-2 Lethal Infection.docx

SARS-CoV-2疫苗研究

免疫原性优化

An effective COVID-19 vaccine against broad SARS-CoV-2 variants is still an unmet need. In the study, the vesicular stomatitis virus (VSV)-based vector was used to express the SARS-CoV-2 Spike protein

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Vaccine based on immune evasion mutations integrated RBD protein have broad protection against SARS-CoV-2 [mRNA-seq]. Vaccine based on immune evasion mutations integrated RBD protein have broad protection against SARS-CoV-2 [mRNA-seq]

SARS-CoV-2疫苗研究

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Variants of SARS-CoV-2 continue to emerge and evade immunity, resulting in breakthrough infections in vaccinated populations. Continued vaccination with vaccines based on the antigens of newly emerged

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A non-transmissible live attenuated SARS-CoV-2 vaccine

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Live attenuated vaccines (LAV) administered via the mucosal route may offer better control of the COVID-19 pandemic than non-replicating vaccines injected intramuscularly. Conceptionally, LAV have sev

NIAID Data Ecosystem40

UB-612 Multitope Vaccine Targeting SARS-CoV-2 Spike and Non-Spike Proteins Provides Broad and Durable Immune Responses

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