Acute Respiratory Distress Syndrome

This study examined the relationship between clinical and biological markers with mortality, long-term outcomes, and new morbidities among survivors of acute respiratory distress syndrome (ARDS). This prospective longitudinal observational cohort study attempted to characterize prognostic and predictive biomarkers and provide a link between these biomarkers and the development of clinically relevant clinical outcomes. The molecular phenotypes defined and knowledge acquired is intended to lead to development of precision medicine strategies targeting therapeutic agents to patients with specific molecular phenotypes or biomarker patterns. The study found that children with ARDS are at risk for worsening health-related quality of life and functional status, which can persist up to nine months after their illness.