Action potential evoked dendritic calcium signals in the medial superior olive (MSO) during development

Dataset underlying the analysis of dendritic calcium signals evoked by somatic action potentials in MSO neurons during development (postnatal day 10 - 60). The data includes recordings from Mongolian gerbils (Meriones unguiculatus) raised in a normal acoustic environment and in omnidirectional white noise. Linked paper: Franzen DL, Gleiss SA, Kellner CJ, Kladisios N, Felmy F. Activity-Dependent Calcium Signaling in Neurons of the Medial Superior Olive during Late Postnatal Development. J Neurosci. 2020 Feb 19;40(8):1689–700. https://doi.org/10.1523/JNEUROSCI.1545-19.2020. Files included: A folder entitiled data containing: The imaging files (.nix) (1 file per imaged neuron). NIX files contain the kymograph data extracted from a ROI in the raw images along with the metadata. The imaging kymographs and associated .nix files were created with the CaManager: ImageJ Plugin For Ca²⁺ Imaging. An excludes.csv file that contains cells/trials to be excluded (e.g. recording error, movement, difficulty in tracing) A Megatable_C.csv file containing the electrophysiological data corresponding to imaged cells A .nix intermediate analysis file for default parameters A .csv file with the combined electrophysiological and imaging data for default parameters Several .xlsx files with the single cell data in Figures 2C, 2D, 2F. Jupyter notebook: The CaJupyter GitHub repository contains a Jupyter notebook with a step-by-step guide of the analysis. It also allows for further exploration of the data. See also: The original analysis code (without adaptations for the Jupyter notebook and Python 3) can be found at CaAnalysis: Analysis Toolbox for Ca²⁺ Imaging. More information on NIX can be found at this link.