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An aniline-substituted bile salt analog protects both mice and hamsters from multiple Clostridioides difficile strains

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NIAID Data Ecosystem2026-03-12 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP330057
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资源简介:
Bile salt analogs prevented spore germination of various Clostridioides difficile strains in vitro. Mice exhibited heterogeneity of CDI signs severity among C. difficile isolates tested. Bile salt analogs protected mice from CDI signs caused by several C. difficile isolates. An aniline-substituted bile salt analog prevented CDI in both mice and hamsters.
创建时间:
2021-08-04
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