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We developed an enhanced fusion variant, makes it an effective CRISPRa tool
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2024-03-20
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Ischemic stroke (IS) is one of the main causes of morbidity and disability worldwide due to its complex mechanism. Anemia was characterized as a risk factor of IS because the direct connection between
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In vivo multiplexed gene activation via improved Cas12a
To evaluate the specificity of CRISPR activation by vgdCas12a on a genome-wide scale, we carried out whole-transcriptome RNA-seq of HEK293T cells with the TRE3G-GFP reporter transfected with either WT
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Number of DEGs related to hemoglobin found by four methods.
Number of DEGs related to hemoglobin found by four methods.
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Data from: Hemocyanin gene family evolution in spiders (Araneae), with implications for phylogenetic relationships and divergence times in the infraorder Mygalomorphae
Hemocyanins are multimeric copper-containing hemolymph proteins involved in oxygen binding and transport in all major arthropod lineages. Most arachnids have seven primary subunits (encoded by paral
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Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex
Integration of the HIV-1 provirus in the host genome ensures a persistent supply of latently infected cells. This latent reservoir is recalcitrant to antiretroviral therapy (ART) making lifelong treat
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