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RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells

ChEBI2016-03-29 更新2026-07-12 收录

胚胎表观遗传调控

多能性维持机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-79655 数据链接链接失效反馈

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资源简介：

RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells

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创建时间：

2016-03-29

胚胎表观遗传调控

基因组印记

Genomic imprinting and X chromosome inactivation (XCI) require epigenetic mechanisms to direct allele-specific expression. Despite their critical roles in embryonic development, how universal epigenet

NIAID Data Ecosystem70

DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries. DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries

胚胎表观遗传调控

CTCF染色质边界调控

The interplay of DNA (de)methylation and the architectural chromatin protein CTCF is an important regulator of cellular differentiation, but molecular mechanisms determining differential CTCF binding

NIAID Data Ecosystem70

Dnmt1 binds and represses genomic retroelements via DNA methylation in mouse early embryos (ChIP-seq)

胚胎表观遗传调控

逆转录元件

Genome-wide passive DNA demethylation in cleavage-stage mouse embryos is related to the cytoplasmic localization of the maintenance methyltransferase DNMT1. However, recent studies provided evidence o

NIAID Data Ecosystem30

Expression regulation by RYBP in mouse embryonic stem cells

胚胎表观遗传调控

Polycomb复合物功能研究

Polycomb repressive complexes (PRCs) are important chromatin regulators of ES cell function. RYBP binds Polycomb H2A monoubiquitin ligases Ring1A and Ring1B, and has been suggested to participate in l

NIAID Data Ecosystem70

Mus musculus Genome sequencing and assembly and Transcriptomics

胚胎表观遗传调控

重复序列沉默

SETDB1 is a key lysine methyltransferase (KMT) required in embryonic stem cells (ESCs), where it silences transposable elements and DNA repeats via histone H3 lysine 9 tri-methylation (H3K9me3), indep

NIAID Data Ecosystem40

RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells

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