Retroviral Vectors Pseudotyped with Lymphocytic Choriomeningitis Virus
收藏PubMed Central2026-05-16 收录
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Pseudotyping can improve retroviral vector stability and transduction efficiency. Here, we describe a novel pseudotype of murine leukemia virus packaged with lymphocytic choriomeningitis virus (LCMV). This pseudotype was stable during ultracentrifugation and infected several cell lines from different species. Moreover, LCMV glycoproteins were not cell toxic.
