Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with an Inhibitor 30a and GRIP Peptide
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Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with an Inhibitor 30a and GRIP Peptide Descriptor: DI(HYDROXYETHYL)ETHER, Estrogen receptor, Grip peptide, ... Authors: Min, J, Hu, H.B, Yang, Y, Dong, C.E, Zhou, H.B, Chen, C.-C, Guo, R.-T. Deposit date: 2022-06-23 Release date: 2023-04-26 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Structure-guided identification of novel dual-targeting estrogen receptor alpha degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer. Eur.J.Med.Chem., 253, 2023
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2022-06-23
