Tankyrase2 catalytic domain in complex with K-476
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Tankyrase2 catalytic domain in complex with K-476 Descriptor: 5-[3-[[1-(6,7-dimethoxyquinazolin-4-yl)piperidin-4-yl]methyl]-2-oxidanylidene-4H-quinazolin-1-yl]-2-fluoranyl-benzenecarbonitrile, Poly [ADP-ribose] polymerase tankyrase-2, SULFATE ION, ... Authors: Takahashi, Y, Suzuki, M, Saito, J. Deposit date: 2020-06-22 Release date: 2021-05-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The dual pocket binding novel tankyrase inhibitor K-476 enhances the efficacy of immune checkpoint inhibitor by attracting CD8 + T cells to tumors. Am J Cancer Res, 11, 2021
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2020-06-22
