Table S4. Results of the human genome-scale sgRNAiBAR library screening at different MOI for the cytotoxicity of TcdB using conventional MAGeCK analysis. Table S5. Results of the human genome-scale sg
Relative sensitivity to genotoxic treatments in respect to other mutants and the control strain cw15-302 arg2 (+++ high sensitivity, ++ intermediate sensitivity, + mild sensitivity, −no sensitivity).
Gene expression biomarkers are now available for application in the identification of genotoxic hazards. The TGx-DDI transcriptomic biomarker can accurately distinguish DDI from non-DDI exposures base
The conventional battery for genotoxicity testing is not well suited to assessing the large number of chemicals needing evaluation. Traditional in vitro tests lack throughput, provide little mechanist
