Dataset on changes in the gut microbiome in vancomycin-treated type 1 diabetic mice after transferring faecal material from healthy donor mice

In this study, streptozotocin-induced diabetic mice were treated with vancomycin (T1DV) to disturb the gut microbiota for 7 weeks. Then, we transferred fecal material from healthy donor mice (COND) to T1DV recipients for 14 days. During fecal microbiota transplantation, faecal samples were collected at 0, 7 and 14 days and analyzed by using a 16S rRNA gene sequencing approach to examine changes in the gut microbiome. This study is submitted to Microbiome. Hong Zheng, Pengtao Xu, Qiaoying Jiang, Qingqing Xu, Yafei Zheng, Junjie Yan, Hui Ji, Jie Ning¹, Xi Zhang, Chen Li, Limin Zhang, Yuping Li, Xiaokui Li, Weihong Song, and Hongchang Gao. (2021). Depletion of acetate-producing bacteria from the gut microbiota facilitates cognitive impairment through the gut-brain neural mechanism in diabetic mice.