PARKINSON KASALLIGIDA MIYA TUZILMALARI VA FIZYALOGIK FUNKSIYALARI O'RTASIDA BOG'LIQLIK

Ushbu maqolada Parkinson kasalligida miyaning anatomik tuzilishi va fiziologik funksiyalari o‘rtasidagi o‘zaro bog‘liqlik yoritilgan. Inson harakat faoliyatini boshqarishda muhim rol o‘ynaydigan bazal yadrolar va xususan substantia nigra tuzilmasining degenerativ o‘zgarishlari tahlil qilinadi. Kasallikning rivojlanishida dopamin ishlab chiqaruvchi neyronlarning yemirilishi asosiy omil bo‘lib, bu holat asab impulslarining uzatilishida fiziologik uzilishlar keltirib chiqaradi. Natijada harakat sekinlashuvi, mushak rigidligi va tremor kabi klinik belgilar yuzaga keladi. Maqolada Parkinson kasalligi misolida anatomiya va fiziologiya fanlarining uzviy bog‘liqligi ilmiy asosda tahlil qilingan hamda bu bog‘liqlikni tushunish kasallikni davolash va erta tashxis qo‘yishdagi ahamiyati ko‘rsatib o‘tilgan. Annotation: This article highlights the interrelationship between the anatomical structure and physiological functions of the brain in Parkinson’s disease. It analyzes the degenerative changes in the basal ganglia, particularly in the substantia nigra, which play a crucial role in controlling human motor activity. The main factor in the development of the disease is the degeneration of dopamine-producing neurons, which leads to physiological disruptions in the transmission of nerve impulses. As a result, clinical symptoms such as bradykinesia (slowness of movement), muscle rigidity, and tremor appear. The article scientifically examines the close connection between anatomy and physiology using Parkinson’s disease as an example and emphasizes the importance of understanding this relationship for effective treatment and early diagnosis.