PRC1 directs PRC2-H3K27me3 deposition to shield adult spermatogonial stem cells from differentiation

NIAID Data Ecosystem2026-05-01 收录

干细胞分化

PRC复合物表观遗传调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE221944 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-03-18

多参量集成控制神经组织芯片研究

神经组织芯片

干细胞分化

通过在集成了传感与调控功能的微芯片上培养细胞，对其所处环境的进行物理或化学调控，实现从干细胞到神经细胞、从单个神经元到神经网络的可控培养；对微芯片上的细胞进行高分辨率电信号或神经递质信号的实时动态监测，研究干细胞神经元定向分化过程中的变化特征，建立基于微纳传感的神经组织芯片新技术体系，实现神经传导及应答功能的体外构建。研究环境因素、外加场等理化调控参数在干细胞分化过程中的作用；研究外加电信号和神经

干细胞与再生医学数据中心2023-06-14 更新120

A human pluripotent stem cell model of FSHD-affected skeletal muscles. Homo sapiens

肌营养不良模型

干细胞分化

Facioscapulohumeral muscular dystrophy (FSHD) represents a majorunmet clinical need arising from the progressive weakness and atrophy of skeletal muscles. The dearth of adequate experimental models ha

NIAID Data Ecosystem90

Hypoxia Promotes Dopaminergic Differentiation of Mesenchymal Stem Cells and Shows Benefits for Transplantation in a Rat Model of Parkinson’s Disease

干细胞分化

帕金森病细胞治疗

Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into dopaminergic (DAergic) neurons, which is one of the major cell types damaged in Parkinson’s disease (PD). For this r

NIAID Data Ecosystem70

Additional file 1: of Sequential stimulation with different concentrations of BMP4 promotes the differentiation of human embryonic stem cells into dental epithelium with potential for tooth formation

干细胞分化

牙上皮细胞形成

Table S1. Presenting the primer used for qRT-PCR. (XLS 27 kb)

NIAID Data Ecosystem100

Additional file 2: of Biphasic modulation of insulin signaling enables highly efficient hematopoietic differentiation from human pluripotent stem cells

干细胞分化

基因表达分析

Table S7. Q-PCR primers used in this study (XLSX 11 kb)

DataCite Commons2024-02-07 更新80