Crystal structure of human Pim-1 kinase in complex with an azaspiro pyrazinyl-indazole inhibitor.
收藏Protein Data Bank Japan2023-12-27 更新2026-03-21 收录
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Crystal structure of human Pim-1 kinase in complex with an azaspiro pyrazinyl-indazole inhibitor. Descriptor: 3-{6-[(4R)-6-azaspiro[2.5]oct-4-yloxy]pyrazin-2-yl}-5-(2,6-difluorophenyl)-1H-indazole, GLYCEROL, Serine/threonine-protein kinase pim-1 Authors: Mohr, C. Deposit date: 2014-10-25 Release date: 2015-02-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
创建时间：
2014-10-25
