Crystallographic projects at Structural Biology Core Facility, JU - bringing the state of art support to the users in need. Continuation 202

The Structural Biology Core Facility was established to support scientists, mostly working in Kraków, who want to supplement their original research with knowledge of the details of structure of the molecules under study. In spite of growing capabilities of CryoEM techniques macromolecular crystallography (MX) remains a method of choice for experimental structure determination and is particularly useful in ligand-screening campaigns. Our goal is to support research groups during all stages from the experiment planning, through crystallisation, crystal fishing, data collection and structure determination, refinement and interpretation of results. Brilliant ESRF beamlines are the main source of our X-ray diffraction images and were proved instrumental in many projects, both completed and ongoing.