Dammarane-Type Triterpenoids from Gentianella azurea
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https://figshare.com/articles/dataset/Dammarane_Type_Triterpenoids_from_i_Gentianella_azurea_i_/2289166
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Thirteen new dammarane-type triterpenoids (1–13) and four known analogues, gentirigenic acid (14) and the gentirigeosides A, B, and E (15–17), were isolated from Gentianella azurea. Their structures were elucidated by detailed analysis of the NMR, MS, and X-ray crystallographic data. This is the first report of dammarane-type triterpenoids in the Gentianella genus. In addition, the known structures of gentirigenic acid (14) and the gentirigeosides A, B, and E (15–17) were revised based on the X-ray diffraction analysis. Gentirigeoside A (15) was found to inhibit nitric oxide production in RAW 264.7 macrophages with an IC50 value of 6.6 ± 2.1 μM.
创建时间：
2016-02-17
