Experimental data for: Environmental detection of amoxicillin using a molecularly imprinted graphene oxide-polyethylenimine electrochemical sensor

In this work, we report the development of a novel, low-cost, and highly selective electrochemical sensor for the indirect detection of amoxicillin (AMX), based on a glassy carbon electrode (GCE) modified with graphene oxide (GO) functionalized by a molecularly imprinted polyethyleneimine polymer (GO-MIP). The GO-PEI composite was synthesized via epoxide ring-opening chemistry and imprinted with AMX to generate selective recognition cavities. The sensor's performance was characterized using cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS). The proposed GO-MIP sensor exhibited high sensitivity and selectivity for AMX, with a limit of detection (LOD) of 0.52 µM in standard solutions and 5,06 µM in environmental water samples. The proposed sensor represents the first application of a molecularly imprinted polyethyleneimine-functionalized graphene oxide composite for AMX detection. It combines low cost, ease of fabrication, and high selectivity, making it a promising tool for environmental monitoring of antibiotic contaminants.