Studies of gene expression and gene ontology on Hopx null mouse embryonic cortex.. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA784788
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In order to determine whether the Hopx protein plays a functional role in regulating fate determination of cortical NPs, we constructed a mutant mouse strain using CRISPR-Cas9 strategy. The mutated Hopx contained an extra nucleotide after the normally 18th base of the coding sequence and thus resulted in a frame shift. We then analyzed the differential expressed genes (DEGs) between wild-type and mutant mice at E16.5.
创建时间：
2021-11-30
