Crystal structure of human BRD4(1) in complex with CN210 (compound 19)
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Crystal structure of human BRD4(1) in complex with CN210 (compound 19) Descriptor: 1-(4-{6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-[(3S)-3-phenylmorpholin-4-yl]quinazolin-2-yl}-1H-pyrazol-1-yl)-2-methylpropan-2-ol, Bromodomain-containing protein 4, GLYCEROL Authors: Nadupalli, A, Fontano, E, Connors, C.R, Chan, S.G, Olland, A.M, Lakshminarasimhan, D, White, A, Suto, R.K. Deposit date: 2018-08-28 Release date: 2019-04-03 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Lead optimization and efficacy evaluation of quinazoline-based BET family inhibitors for potential treatment of cancer and inflammatory diseases. Bioorg. Med. Chem. Lett., 29, 2019
创建时间：
2018-08-28
