CALR frameshift mutations accelerate maturation of megakaryocytes in MPN patient-derived iPS cells
收藏NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP333390
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资源简介：
In this dataset, we compare the gene expression data of induced pluripotent stem (iPS) cell-derived CD61+ megakaryocytes carrying heterozygous or homozygous Calreticulin (CALR) ins5 mutations or the CALR wildtype gene. Overall design: 9 samples; Three biological replicates were analyzed per genotype. Het - heterozygous CALRins5 mutation; Hom - homozygous CALR mutation; WTcr - CALR wildtype generated by CRISPR/Cas9 using the respective mutated clone.
创建时间：
2021-12-01
