Gene expression profiles of the mouse jejunum in a bidirectional nutrient supply model

The small intestine is the primary organ for nutrient sensing and absorption, in order to more comprehensively reveal the nutrient sensing and response of intestinal cells, we used Bulk RNA sequencing to reveal the effects of enteral and serosal nutrients on the intestinal tract in a bidirectional nutrient supply mode. Overall design: To examine the response of different types of cells in the jejunum to the bidirectional nutrition, mice were treated with sham, TPN, or starvation for 24 h, and then 5 cm of jejunal tissue was harvested.