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Extensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells

NIAID Data Ecosystem2026-03-08 收录

纳米材料毒性

线粒体功能障碍

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63580 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2015-04-03

纳米材料毒性

基因表达分析

We investigated the impacts of transition metal oxide (TMO) lithium-ion battery cathode nanomaterial, lithium cobalt oxide (LCO), on gene expression in the larvae of a model sediment invertebrate Chir

NIAID Data Ecosystem20

Supplementary Data File 5: Experimental allocation.

帕金森病发病机制

线粒体功能障碍

Experimental allocation of subjects in the study "Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson’s disease"

Figshare2025-02-19 更新10

Inflammation in the pleural cavity following injection of multi-walled carbon nanotubes is dependent on their characteristics and the presence of IL-1 genes

纳米材料毒性

膜炎症机制

Upon inhalation, multi-walled carbon nanotubes (MWCNTs) may reach the subpleura and pleural spaces, and induce pleural inflammation and/or mesothelioma in humans. However, the mechanisms of MWCNT-indu

NIAID Data Ecosystem10

Data_Sheet_1_Proteomic profiling reveals mitochondrial dysfunction in the cerebellum of transgenic mice overexpressing DYRK1A, a Down syndrome candidate gene.docx

线粒体功能障碍

蛋白质组学分析

IntroductionDYRK1A is a dual-specificity kinase that is overexpressed in Down syndrome (DS) and plays a key role in neurogenesis, neuronal differentiation and function, cognitive phenotypes, and aging

NIAID Data Ecosystem10

Alteration of in vivo gene expression in Drosophila intestinal stem cells after OXPHOS disruption and the role of FOXO in it.

干细胞基因表达

线粒体功能障碍

To investigate the in vivo gene expression changes in Drosophila intestinal stem cells (ISCs) when OXPHOS is disrupted and the role of FOXO in regulating this process, we dissected midguts from 4 gr

NIAID Data Ecosystem10

Extensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells

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