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Crystal structure of LSD1-CoREST in complex with a tranylcypromine derivative (MC2584, 13b)

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Crystal structure of LSD1-CoREST in complex with a tranylcypromine derivative (MC2584, 13b) Descriptor: 3-{4-[(PHENYLCARBONYL)AMINO]PHENYL}PROPANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ... Authors: Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A. Deposit date: 2010-03-31 Release date: 2010-05-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2. J.Am.Chem.Soc., 132, 2010
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2010-03-31
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