Data Files, Chronotherapy

Output of chronotherapy simulated with NetLogo computer program Colon_Crypt_Model_073120. The model is described in a separate file. Each data file is the result of cytotoxic chemotherapy during a different 4 hour period during the day.The file names (Data Analysis…) indicate the date that they were generated (073120 is Aug. 31, 2020), the time step that circadian cell proliferation was initiated (Circad), the time step the chemotherapy was initiated (Chemo), and the time steps (Phase) that chemotherapy was active.Data in each column include the following, A: run number, with the number of time steps when mutants were initiated and the number of time steps that chemotherapy was initiated; B: whether or not the mutants overflowed the crypt and the mutants were not eliminated from the crypt (cured); C: the time step at which the mutants were eliminated from the crypt (cured); D: time steps between the time that chemotherapy was on and the time that mutants were cured; E: time to cure mutants in hours, assuming one time step equals four hours.; F: time to cure mutants in days; G: time of day, in hours, when chemotherapy was initiated.A forthcoming publication will describe the computer program and simulation results of circadian-timed chemotherapy.