Immune checkpoint blockade (ICB) therapy has revolutionized the treatment of multiple cancers, but the majority of patients remain refractory due to impaired MHC-I expression. Although the combination

NIAID Data Ecosystem40

Binding affinity of common iNOS inhibitors to nitric oxide synthase (NOS) human isoforms.

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酶抑制剂结合力

Binding affinity of common iNOS inhibitors to nitric oxide synthase (NOS) human isoforms.

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Additional file 5 of Analysis of H3K4me3 and H3K27me3 bivalent promotors in HER2+ breast cancer cell lines reveals variations depending on estrogen receptor status and significantly correlates with gene expression

乳腺癌表观遗传学

组蛋白修饰与基因表达

Additional file 5: Supplementary Table 5. The list of genes in the Estrogen Signaling pathway according to KEGG, with their histone trimethylation status and corresponding gene expression (in FPKM).

Figshare2020-07-04 更新50

Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII

碳酸酐酶抑制剂

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To get a better understanding of the possibility of developing selective carbonic anhydrase (CA) inhibitors, interactions between 17 benzenesulphonamide ligands and 6 human CAs (full-length CA I, II,

NIAID Data Ecosystem40

Expression profiling of MDA-MB-231 breast cancer cells treated with DOT1L inhibitors and siDOT1L

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