pat-2 promotes apoptotic cell engulfment in a pathway distinct from previously known pathways.
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aThe number of cell corpses in each genotype was scored at the indicated embryonic stage.bNon-transgenic progeny of ced-1(e1735); unc-79(e1068) pat-2(st567); Ex[Ppat-2pat-2::gfp] mothers.cNon-transgenic progeny of unc-79(e1068) pat-2(st567); ced-5(n1812); Ex[Ppat-2pat-2::gfp] mothers.dNon-transgenic progeny of ced-1(e1735); unc-79(e1068) pat-2(st567); ced-5(n1812); Ex[Ppat-2pat-2::gfp] mothers.eHomozygous progeny of pat-3(st564)/qC1 dpy-19(e1259) glp-1(q339) heterozygous mothers.fHomozygous progeny of cdc-42(gk388)/mIn1[mIs14 dpy-10(e128)] heterozygous mothers. Double mutants were compared to the corresponding single mutants (*pp##p15 embryos per stage.
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2015-12-02
