Primate lentiviruses, including human immunodeficiency virus type 1 (HIV-1) type 2 (HIV-2) and the simian immunodeficiency viruses (SIVs), cause infections that result in persistent lifelong viral rep
Pyroptosis mediated by Caspase-1/GSDMD is a crucial antiviral defense. We reveal that PRRSV nucleocapsid protein (N) subverts this pathway by recruiting host ubiquitination machinery. PRRSV N binds Ca
Theiler's virus is a neurotropic picornavirus responsible for chronic infections of the central nervous system. The establishment of a persistent infection and the subsequent demyelinating disease tri
