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RNA-Seq of Whole Blood from Pediatric Sickle Cell Anemia (SCA) Patients

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DataCite Commons2026-04-09 更新2026-05-04 收录
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https://gen3.biodatacatalyst.nhlbi.nih.gov/discovery/phs002687.v1.p1.c1/
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The aim of this study is to define the immune cell transcriptome by next generation RNA sequencing in blood from individuals with SCA, in comparison to healthy African American controls. This study has a cross-sectional case-control design. We will compare the transcriptome profiles of blood mononuclear cells from healthy age-matched African American children without cardiovascular disease or risk factors (&#8220;Controls&#8221;) to those of children with SCA, age 5 -21 years, who are not receiving chronic red blood cell transfusions or hydroxyurea therapy to identify genes that are differentially expressed in SCA.&nbsp; <br>
提供机构:
NHLBI BioData Catalyst
创建时间:
2026-03-09
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