MOESM9 of Global impact of somatic structural variation on the DNA methylome of human cancers

Additional file 9. Related to Fig. 5. SSV associations with translocated active in vivo-transcribed enhancers. For the enhancer-related analyses of Fig. 5b, the Andersson et al. tissue- or cell-specific enhancer subsets as applied to each TCGA or ICGC project are listed. Results include the subset of SSV breakpoint associations involving the translocation of an active, in vivo-transcribed enhancer within 0.5â Mb of the gene (where the unaltered gene had no enhancer within 1â Mb), for both the entire set of SSV breakpoint associations occurring 0-500â kb upstream of a gene and with breakpoint mate on the distal side from the gene (for cases with WGS), as well as for the subset of SSV breakpoint associations involving altered gene expression or CGI methylation.