PLOS Comput. Biol. "Biophysically detailed mathematical models of multiscale cardiac active mechanics": datasets

This repository contains the data accompanying the PLOS Computational Biology paper "<em>Biophysically detailed mathematical models of multiscale cardiac active mechanics</em>", by Francesco Regazzoni, Luca Dedè and Alfio Quarteroni. It contains the following datasets: <strong>steady_state.csv</strong>: steady-state active tension for constant calcium concentration and sarcomere length (Figs. 11, 12, 13 ,14). <strong>isometric_twitches.csv</strong>: active tension transients in isometric conditions (Figs. 15, 16, 17). <strong>force_velocity_relationship.csv</strong>: force-velocity relationship at different calcium concentrations and sarcomere lenghts (Fig. 18). <strong>fast_transient_response.csv</strong>: tension-elongation curve after a fast step in length (Fig. 19). CSV headers refer to the following variables (and measure units): <strong>Ca</strong> (<em>μM</em>): intracellular calcium concentration. <strong>SL</strong> (<em>μm</em>): sarcomere length. <strong>active_tension</strong> (<em>kPa</em>): active tension. <strong>Delta_L</strong> (<em>nm/hs</em>): step length. <strong>velocity</strong> (<em>hs/s</em>): shortening velocity. <strong>time</strong> (<em>s</em>): time.