Aging induces region-specific functional decline across the brain. The cerebellum, critical for motor coordination and cognitive function, undergoes significant structural and functional changes with

NIAID Data Ecosystem40

Single-cell RNA-sequencing of Platynereis dumerilii larval brain cells. Single-cell RNA-sequencing of Platynereis dumerilii larval brain cells

单细胞空间转录组学

脑进化发育生物学

Understanding cell type identity in complex tissues or organisms requires integration of each cell’s expression profile with its spatial location within the tissue under study. We developed a high-thr

NIAID Data Ecosystem40

Additional file 4 of Single-cell spatial transcriptomic analysis reveals common and divergent features of developing postnatal granule cerebellar cells and medulloblastoma

单细胞空间转录组学

髓母细胞瘤分子病理

Additional file 4: Supplementary Table S3. Monocle 3 module genes. Related to Fig. 2.

Figshare2024-02-14 更新50

Integrative single cell and spatial transcriptomic analysis reveal reciprocal microglia-plasma cell crosstalk in the mouse brain during chronic Trypanosoma brucei infection. Integrative single cell and spatial transcriptomic analysis reveal reciprocal microglia-plasma cell crosstalk in the mouse brain during chronic Trypanosoma brucei infection

神经免疫学

单细胞空间转录组学

Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasite Trypanosoma brucei and induces profound reactivity of glial cells and neuroinflammation when the parasites colo

NIAID Data Ecosystem40

Additional file 1 of Acute ischemia induces spatially and transcriptionally distinct microglial subclusters

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