Gene and pathways affected by CAG-repeat RNA-based toxicity in Drosophila

ChEBI2011-11-22 更新2026-07-21 收录

神经退行性机制

果蝇遗传学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-31875 数据链接链接失效反馈

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Gene and pathways affected by CAG-repeat RNA-based toxicity in Drosophila

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2011-11-22

Examination of gene expression in cerebellum and hippocampus for mouse C57BL/6J WT and nmf205-/-

神经退行性机制

细胞应激通路

Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathw

NIAID Data Ecosystem100

Senataxin, the helicase mutated in AOA2 and ALS4, plays a role in autophagy regulation [HTS]

神经退行性机制

自噬调控通路

Senataxin (SETX) is an RNA/DNA helicase that has been implicated in transcriptional regulation and the DNA damage response, through resolution of R-loop structures. Mutations in SETX result in either

NIAID Data Ecosystem20

Drosophila orthologues of candidate human obesity genes.

肥胖基因直系同源

果蝇遗传学

The 24 Drosophila orthologues of 27 human genes with rare variants in obese patients, which were chosen for further study. The DIOPT score, TRiP RNAi line (except itpr (NIG line), and the function of

NIAID Data Ecosystem20

AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons

神经退行性机制

功能障碍研究

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem40

Rescue of D. melanogaster/D. mauritiana hybrid male lethality by D. melanogaster Lhr − deletions.

果蝇遗传学

基因存在/缺失分析

D. melanogaster females with the designated deletions were mated to D. mauritiana males at 18°. The small number of live males recovered are likely patroclinous exceptions, that is Xmau/O. Pharate adu

NIAID Data Ecosystem20

Gene and pathways affected by CAG-repeat RNA-based toxicity in Drosophila

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