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RNA-seq profiling of CD34-high and CD34-low fibroblasts from mouse mammary tumors

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP533467
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A mouse model of Wnt1-driven mammary tumors was generated. Specifically, PdfraH2B-GFP mice (C57BL/6) were crossed to MMTV-cre(A)-Wnt1 transgenic mice (FVB/J) to generate the raGFP-Wnt1 mouse line. CD34-high and CD34-low fibroblast cells were then FACS sorted from mammary tumors from the raGFP-Wnt1 mice. Overall design: CD34-high and CD34-low fibroblast cells were sorted from three raGFP-Wnt1 tumors, to create six samples in total.
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2025-07-23
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