Antimicrobial Susceptibilities of Clinical Desulfovibrio Isolates

The antimicrobial susceptibilities of 16 clinical isolates of Desulfovibrio spp. were determined. All or most isolates were susceptible to imipenem (MIC(90) [MIC at which 90% of the isolates tested were inhibited], 0.5 μg/ml), metronidazole (MIC(90), 0.25 μg/ml), clindamycin (MIC(90), 4 μg/ml), and chloramphenicol (MIC(90), 16 μg/ml) but were resistant or intermediate to penicillin G (MIC(90), 64 μg/ml), piperacillin (MIC(90), 256 μg/ml), piperacillin-tazobactam (MIC(90), 256 μg/ml), cefoxitin (MIC(90), >256 μg/ml), and cefotetan (MIC(90), 64 μg/ml). Among isolates with decreased susceptibility to β-lactams (n = 15), only six were β-lactamase positive and susceptible to amoxicillin-clavulanate and ticarcillin-clavulanate.