Depalmitoylation of eNOS
收藏reactome.org2025-03-26 收录
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Increases in intracellular calcium and calmodulin stimulate depalmitoylation of eNOS by acyl protein thioesterase 1, which displaces eNOS from the membrane. This might be a mechanism to downregulate NO production following intense stimuli.
细胞内钙离子和钙调蛋白的增加,通过酰基蛋白硫酯酶1介导,刺激内皮型一氧化氮合酶(eNOS)的脱棕榈酰化,从而将eNOS从细胞膜上移除。这可能是针对强烈刺激后下调一氧化氮(NO)产生的一种机制。
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